The Samson Plan
Everything we did — organized for you.
Core Medications
The foundation of the Samson Plan involves two primary medications that have shown promising results in cancer treatment: ivermectin and fenbendazole. These medications, when used appropriately and under veterinary supervision, may help slow or even reverse cancer progression in some dogs.
We've organized detailed information about dosing, administration, and cycling schedules to help you discuss these options with your veterinarian.
| Medication | Dosage & Frequency | How to Give / Tips | Mechanism of Action |
|---|---|---|---|
Fenbendazole | 50 mg/kg daily 3 days on / 4 days off Capped at 2000 mg/day | Mix with wet food with strong aroma (e.g., tripe) For blind dogs: Use consistent verbal cues before administration | Disrupts microtubules Triggers apoptosis Starves cancer cells |
Ivermectin | 0.22 mg/kg daily Capped at 12 mg/day | Give orally with food Available as injectable (given orally) or paste Start with lower dose and gradually increase | Autophagy Ferroptosis Immune priming Metabolism blocker |
Timing & Cycling
Fenbendazole Cycle
Give fenbendazole for 3 consecutive days, then take a 4-day break. Repeat this cycle continuously.
Daily Administration
- AM:Ivermectin with breakfast
- AM/PM:Fenbendazole can be split into two doses if needed
- Empty stomach:
Tips We Learned Giving These to Samson
- 1
Use a mix of goat, beef, and tripe to rotate flavors and hide medications. This prevents "food aversion" that can develop if you always use the same food.
- 2
Set timers and keep a checklist (or use our Tracker page). Consistency is key for effectiveness and helps your dog adapt to the routine.
- 3
Use consistent phrases ("Time for your treat, Samson!") before giving medications. This is especially important for blind dogs who rely on verbal cues.
- 4
Stick to a morning ritual so your dog adapts quickly. For blind dogs, use the same location and approach each time to reduce anxiety.
- 5
For paste medications, use a digital scale to measure accurately. For liquid medications, use a syringe (without needle) for precise dosing.
Ready to Start?
Now that you understand the Samson Plan, you may be ready to discuss it with your veterinarian and consider implementing it for your dog. Remember that every dog is unique, and the plan may need to be adjusted based on your dog's specific needs.
Use our dosage calculator to determine the appropriate dosages for your dog based on their weight, and download or print the plan to share with your veterinarian.